Nucleotides and organophosphates of cardiac, fast, and slow muscles of chick during development


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Radha, E. and Krishnamoorthy, R.V. (1973) Nucleotides and organophosphates of cardiac, fast, and slow muscles of chick during development. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 45 (4). pp. 847-865. ISSN 1096-4959

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Nucleotides like ATP, ADP, AMP and organophosphate, a compd. like creatine phosphate, creatine, and creatinine were estd. in the cardiac, slow anterior latissimus dorsi (ALD) and fast posterior latissimus dorsi (PLD) muscles of the prenatal chick. A decrease in the ATP level and an increase in the ADP​/ATP ratio was obsd. with the advance in development in all muscle types. The increase in ADP level with an increase in development was noted with a complementary increase in the activity of ATP creatine transphosphorylase in all types. A gradual increase in creatine phosphate and a decrease in free phosphate in all the muscle types was recorded. The utilization of ATP as indicated by phosphate potential was suggested to be existing during development by way of increased transphosphorylation. The heart and ALD muscles exhibited similar trends in ATP utilization up to the 16th day. The Ca2+ and Mg2+ activated myofibrillar activity exhibited a decrease with ref. to development. The studies on ocular shortening of glycerinated fibers revealed that the contractility of the fibers progressively increased with development. The ALD fibers are bound to Ca2+ more than that of PLD and heart. The sensitivity of Ca2+ to the fibers changes with development as the PLD fibers become more sensitive:heart fibers lose their sensitivity; and ALD fibers have a mixed nature with ref. to Ca2+ sensitivity.

Item Type: Article
Uncontrolled Keywords: Anterior latissimus dorsi; posterior latissimus dorsi; creatine transphosphorylase; creatine phosphate; phosphate potential; creatinine; creatine; myofibrillar ATPase; glycerinated fibre; ocular shortening; molecular differentiation
Subjects: Faculty of Science > Environmental and Biological Sciences > Zoology
Divisions: Jnana Bharathi / Central College Campus > Department of Zoology
Depositing User: Ms. Sathyavathi N
Date Deposited: 20 Sep 2016 06:33
Last Modified: 20 Sep 2016 06:33

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