Effect of divalent metal ions in membrane permeability modified by polyene antibiotics

Swamy, G.S. and Sullia, S.B. (1974) Effect of divalent metal ions in membrane permeability modified by polyene antibiotics. Indian Journal of Experimental Biology, 12 (3). pp. 296-298. ISSN 0019-5189

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Disks of beet root and potato tuber exhibited increased efflux of betacyanin , carbohydrates, and amino acids on treatment with the polyene antibiotics aureofungin [8065-​41-​6] and hamycin [1403-​71-​0]​. The effect of aureofungin was reversed by calcium [7440-​70-​2] ions in the case of beet root; but calcium ions did not antagonize the effect of hamycin. The effect of calcium ions against aureofungin was not obsd. in potato tuber disks. A combination of aureofungin or hamycin with EDTA [60-​00-​4] caused greater permeability of the membranes than the antibiotics (aureofungin or hamycin) alone, and this effect of the chelating agent was reversed by both calcium and magnesium [7439-​95-​4] ions. Calcium ions apparently have a stabilizing effect on the beet root membrane against aureofungin, and in general, both metal ions contribute to membrane stability by involvment in the structure of the membrane.

Item Type: Article
Subjects: Faculty of Science > Environmental and Biological Sciences > Botany
Divisions: Jnana Bharathi / Central College Campus > Department of Botany
Depositing User: Ms. Sathyavathi N
Date Deposited: 19 Sep 2016 05:04
Last Modified: 19 Sep 2016 05:04
URI: http://eprints-bangaloreuniversity.in/id/eprint/5758

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