Computational identification of conserved miRNAs and their potential targets in French bean (Phaseolus vulgaris)


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Nageshbabu, R. and Jyothi, M.N. and Sharadamma, N. and Rai, D.V. and Devaraj, V.R. (2012) Computational identification of conserved miRNAs and their potential targets in French bean (Phaseolus vulgaris). Research Journal of Pharmaceutical, Biological and Chemical Sciences, 3 (4). pp. 562-568. ISSN 09758585

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MicroRNAs (miRNAs) are a novel growing family of endogenous, small, non- coding, single-stranded RNA molecules directly involved in regulating gene expression at the posttranscriptional level. High conservation of miRNAs in plant provides the foundation for identification of new miRNAs in other plant species through homology alignment. Here, previously known plant miRNAs were BLAST against the Expressed Sequence Tag (EST) database of French bean (Phaseolus vulgaris), and according to a series of filtering criteria, a total of 10miRNAs were identified, and 24potential target genes of them were subsequently predicted, most of which seemed to encode transcription factors or enzymes participating in regulation of development, growth and other physiological processes. Overall, our findings lay the foundation for further researches of miRNAs function inFrench bean.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: microRNA; transcription factor, article; binding affinity; binding site; controlled study; expressed sequence tag; gene function; gene identification; gene targeting; mathematical computing; nonhuman; Phaseolus vulgaris; plant development; plant growth; plant metabolism; prediction; promoter region; RNA binding; sequence analysis
Subjects: Faculty of Science > Environmental and Biological Sciences > Biochemistry
Divisions: Jnana Bharathi / Central College Campus > Department of Biochemistry
Depositing User: Mr. Kirana Kumar D
Date Deposited: 04 Apr 2016 06:09
Last Modified: 04 Apr 2016 06:09

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