Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones under microwave irradiation

Afzal, M.P. and Jayshankara, V.P. (2005) Synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones under microwave irradiation. Indian Journal of Heterocyclic Chemistry, 14 (3). pp. 261-262. ISSN 09711627

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SnCl2.2H2O efficiently catalyzes the three component coupling of β-keto ester, substituted arylaldehyde and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones/thiones, the new protocol for the Biginelli reaction under microwave irradiation works in the absence of solvent, the yields are high and the reaction goes to completion within 20-40 secs.

Item Type: Article
Additional Information: cited By 1
Subjects: Faculty of Science > Pure Sciences > Chemistry
Divisions: Jnana Bharathi / Central College Campus > Department of Chemistry
Depositing User: Mr. Kirana Kumar D
Date Deposited: 22 Feb 2016 06:51
Last Modified: 22 Feb 2016 06:51

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